Serre di Rapolano is a frazione in the comune of Rapolano Terme in the province of Siena, Tuscany, Italy.
It is located on a hill midway between the valleys of the Sentino and Ombrone rivers. Among the prominent buildings are: *Palazzo Gori Martini- 19th-century neo-gothic white marble palace
- Chiesa della Compagnia di Santa Caterina della Misericordia - small oratory with frescoes by Sebastiano Follia and canvases by Astolfo Petrazzi
- Castello di Modanella
- Pieve di Sant'Andreino alle Cave
- Pieve dei Santi Andrea e Lorenzo
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